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Wall Street slips on US-Iran negotiation doubts, Dow down 293 points

Wed Apr 22, 2026 8:12 am JST Market

US stocks fell on April 21, with the DOW JONES INDUSTRIAL AVERAGE declining 293.18 points to 49,149.38, marking a second consecutive session of losses. Reports emerged that US Vice President Vance postponed a visit to Islamabad, Pakistan, for negotiations with Iran. Iran also reportedly notified the US via Pakistan that it would not attend the discussions. Uncertainty surrounding the Iranian situation weighed on sentiment, prompting selling aimed at reducing long positions in major stocks.

MERCK , HONEYWELL INTERNATIONAL , and SHERWIN-WILLIAMS declined, while HIMS & HERS HEALTH and NORTHROP GRUMMAN fell sharply. Meanwhile, UNITEDHEALTH GROUP surged. ORACLE and D.R. HORTON also advanced.

The NASDAQ COMPOSITE INDEX fell 144.43 points to 24,259.96, marking its second straight decline. TESLA , ALPHABET , and APPLE were weak. COINBASE GLOBAL plunged. On the other hand, ADVANCED MICRO DEVICES attracted buying, and ASTERA LABS posted significant gains.

Source: MINKABU PRESS

*Translated by generative AI. Click here for the original article.

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