JCR Pharma signs license agreement with Italfarmaco for commercialization of 'Izcargo' in the U.S., Europe, and other markets
JCR Pharmaceuticals Co., Ltd. <4552> announced after the close on Oct. 2 that it entered into an exclusive licensing agreement with Italian pharmaceutical firm Italfarmaco to develop and commercialize "Izcargo" (generic name: pabinafusp alfa) - a blood-brain barrier-crossing enzyme replacement therapy for Hunter syndrome approved in Japan - covering the United States, Europe, and Latin America.
Izcargo delivers enzymes systemically, including to the brain, via intravenous administration in Hunter syndrome patients. It was approved and launched in Japan in 2021, with a global Phase 3 trial currently underway. JCR Pharma and Italfarmaco previously signed an exclusive licensing agreement in December 2025 to commercialize Duchenne muscular dystrophy treatment "Givinostat" in Japan, with the latest deal further deepening their strategic partnership. Under the agreement, JCR Pharma will receive an upfront payment, milestone payments, royalties, and supply consideration from Italfarmaco.
Source: MINKABU PRESS
*Translated by generative AI. Click here for the original article.
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